Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells.

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells.

DCs express intrinsic cellular defense mechanisms to specifically inhibit HIV-1 replication. Thus, DCs are productively infected only at very low levels with HIV-1, and this non-permissiveness of DCs is suggested to go along with viral evasion. We now illustrate that complement-opsonized HIV-1 (HIV-...

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Main Authors: Wilfried Posch, Marion Steger, Ulla Knackmuss, Michael Blatzer, Hanna-Mari Baldauf, Wolfgang Doppler, Tommy E White, Paul Hörtnagl, Felipe Diaz-Griffero, Cornelia Lass-Flörl, Hubert Hackl, Arnaud Moris, Oliver T Keppler, Doris Wilflingseder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005005
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https://doi.org/10.1371/journal.ppat.1005005

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