Diagnostic algorithm for the detection of carbapenemases and extended-spectrum β-lactamases in carbapenem-resistant Pseudomonas aeruginosa

Diagnostic algorithm for the detection of carbapenemases and extended-spectrum β-lactamases in carbapenem-resistant Pseudomonas aeruginosa

ABSTRACT Pseudomonas aeruginosa can acquire carbapenem resistance through various mechanisms, including genomic mutations leading to the overexpression of efflux pumps, intrinsic AmpC-β-lactamase, and/or reduced permeability, and/or through the acquisition of plasmid-mediated carbapenemases and/or e...

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Bibliographic Details
Main Authors:	Stefano Mancini, Laia Garcia-Verellen, Helena M. B. Seth-Smith, Peter M. Keller, Natalia Kolesnik-Goldmann, Muhammad Ali Syed, Irfan Ullah, Vladimira Hinic, Tim Roloff, Adrian Egli, Oliver Nolte
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-06-01
Series:	Microbiology Spectrum
Subjects:	CRPA carbapenemase production carbapenemase detection ESBL detection
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.03196-24
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