Diagnostic algorithm for the detection of carbapenemases and extended-spectrum β-lactamases in carbapenem-resistant Pseudomonas aeruginosa

Diagnostic algorithm for the detection of carbapenemases and extended-spectrum β-lactamases in carbapenem-resistant Pseudomonas aeruginosa

ABSTRACT Pseudomonas aeruginosa can acquire carbapenem resistance through various mechanisms, including genomic mutations leading to the overexpression of efflux pumps, intrinsic AmpC-β-lactamase, and/or reduced permeability, and/or through the acquisition of plasmid-mediated carbapenemases and/or e...

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Main Authors: Stefano Mancini, Laia Garcia-Verellen, Helena M. B. Seth-Smith, Peter M. Keller, Natalia Kolesnik-Goldmann, Muhammad Ali Syed, Irfan Ullah, Vladimira Hinic, Tim Roloff, Adrian Egli, Oliver Nolte
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:Microbiology Spectrum
Subjects:
CRPA
carbapenemase production
carbapenemase detection
ESBL detection
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03196-24
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https://journals.asm.org/doi/10.1128/spectrum.03196-24

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