Antioxidant evaluation of novel 3-Aryl-5-phenyloxy-1,2,4-oxadiazoles as radical scavengers: Synthesis, characterization, and ADME studies

Antioxidant evaluation of novel 3-Aryl-5-phenyloxy-1,2,4-oxadiazoles as radical scavengers: Synthesis, characterization, and ADME studies

Cell function depends on redox homeostasis, and several diseases are linked to its disruption. The relative amounts of reduced and oxidised glutathione play a major role in controlling redox balance. Redox equilibrium is essential for a number of physiological functions, including protein folding an...

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Bibliographic Details
Main Authors: Mohammed Salah Ayoup, Islam Shawki, Hamida Abdel-Hamid, Doaa A. Ghareeb, Samah Ashraf, Mohamed El-Atawy, Nuha S. Alharbi, Jawaher Y. Al Nawah, Magda M.F. Ismail
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Results in Chemistry
Subjects:
Design
Synthesis
1,2,4-Oxadiazole
Antioxidant
In silico
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715625004916
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