IL‐10 producing type 2 innate lymphoid cells prolong islet allograft survival

IL‐10 producing type 2 innate lymphoid cells prolong islet allograft survival

Abstract Type 2 innate lymphoid cells (ILC2s) are a subset of ILCs with critical roles in immunoregulation. However, the possible role of ILC2s as immunotherapy against allograft rejection remains unclear. Here, we show that IL‐33 significantly prolonged islet allograft survival. IL‐33‐treated mice...

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Bibliographic Details
Main Authors: Qingsong Huang, Xiaoqian Ma, Yiping Wang, Zhiguo Niu, Ruifeng Wang, Fuyan Yang, Menglin Wu, Guining Liang, Pengfei Rong, Hui Wang, David CH Harris, Wei Wang, Qi Cao
Format: Article
Language:English
Published: Springer Nature 2020-10-01
Series:EMBO Molecular Medicine
Subjects:
IL‐10
IL‐33
innate lymphoid cells
islet transplantation
type 1 diabetes
Online Access:https://doi.org/10.15252/emmm.202012305
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https://doi.org/10.15252/emmm.202012305

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