Hspa13 Deficiency Impaired Marginal Zone B Cells Regulatory Function and Contributed to Lupus Pathogenesis

Hspa13 Deficiency Impaired Marginal Zone B Cells Regulatory Function and Contributed to Lupus Pathogenesis

Abstract Dysregulated IL‐10 producing regulatory B cells (Bregs) are associated with the progression of systemic lupus erythematosus. An immunomodulatory role of heat shock proteins (HSPs) is implicated in autoimmune diseases. However, the molecular basis underlying the role of Hspa13 in regulating...

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Bibliographic Details
Main Authors: Chen Xing, Haoran Cui, Ge Li, Xiaoling Liu, Kun Liu, Qing Wen, Xin Huang, Renxi Wang, Lun Song
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
Hspa13
IL‐10
MZ B cells
regulatory B cells
regulatory T cells
SLE
Online Access:https://doi.org/10.1002/advs.202413144
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https://doi.org/10.1002/advs.202413144

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