The decrease in zinc‐finger E‐box‐binding homeobox‐1 could accelerate steroid‐induced osteonecrosis of the femoral head by repressing type‐H vessel formation via Wnt/β‐catenin pathway

The decrease in zinc‐finger E‐box‐binding homeobox‐1 could accelerate steroid‐induced osteonecrosis of the femoral head by repressing type‐H vessel formation via Wnt/β‐catenin pathway

Abstract Background Zinc‐finger E‐box‐binding homeobox‐1 (ZEB1) is predominantly found in type‐H vessels. However, the roles of ZEB1 and type‐H vessels in steroid‐induced osteonecrosis of the femoral head (SONFH) are unclear. Methods Human femoral heads were collected to detect the expression of ZEB...

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Bibliographic Details
Main Authors: Guangyang Zhang, Yuanqing Cai, Jialin Liang, Zhaopu Jing, Wang Wei, Leifeng Lv, Xiaoqian Dang, Qichun Song
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Animal Models and Experimental Medicine
Subjects:
steroid‐induced osteonecrosis of the femoral head
type‐H vessel
Wnt/β‐catenin pathway
zinc‐finger E‐box‐binding homeobox‐1
Online Access:https://doi.org/10.1002/ame2.12507
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https://doi.org/10.1002/ame2.12507

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