MBX-102/JNJ39659100, a Novel Non-TZD Selective Partial PPAR-𝛾 Agonist Lowers Triglyceride Independently of PPAR-𝛼 Activation
MBX-102/JNJ-39659100 (MBX-102) is a selective, partial PPAR-𝛾 agonist that lowers glucose in the absence of some of the side effects, such as weight gain and edema, that are observed with the TZDs. Interestingly MBX-102 also displays pronounced triglyceride lowering in preclinical rodent models and...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/2009/706852 |
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