[18F]-FLT-PET to evaluate how the sequencing of chemotherapies impacts the efficacy of combination treatment in mouse models of triple-negative breast cancer

[18F]-FLT-PET to evaluate how the sequencing of chemotherapies impacts the efficacy of combination treatment in mouse models of triple-negative breast cancer

Introduction: Triple-negative breast cancer (TNBC) lacks targeted therapies due to an absence of biomarkers, making chemotherapy the primary treatment option for early-stage cancer. This study evaluates whether the order and sequence of combination chemotherapy—doxorubicin (DRB) and paclitaxel (PTX)...

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Bibliographic Details
Main Authors: Yun Lu, Jonathan Moye, Adriana V.F. Massicano, Carlos A. Gallegos, Shannon E Lynch, Patrick N. Song, Sharon Samuel, Anna G. Sorace
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
triple-negative breast cancer
doxorubicin
paclitaxel
cell cycle
molecular imaging
immune cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558625000636
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