FOXO1 mediates miR-99a-5p/E2F7 to restrain breast cancer cell proliferation and induce apoptosis

Abstract Background FOXO1 is known to act as a tumor suppressor gene in breast cancer, but its exact mechanism of action remains unclear. Objective This study aimed to clarify how FOXO1 suppresses breast cancer cell proliferation and induces apoptosis. Methods Breast cancer cell lines were generated...

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Bibliographic Details
Main Authors: Ying Zhang, Haili Wang, Yiliang Wang, Bo Ma
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-025-14111-1
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