Bioinformatic Insights and XGBoost Identify Shared Genetics in Chronic Obstructive Pulmonary Disease and Type 2 Diabetes

Bioinformatic Insights and XGBoost Identify Shared Genetics in Chronic Obstructive Pulmonary Disease and Type 2 Diabetes

ABSTRACT Background The correlation between chronic obstructive pulmonary disease (COPD) and Type 2 diabetes mellitus (T2DM) has long been recognized, but their shared molecular underpinnings remain elusive. This study aims to uncover common genetic markers and pathways in COPD and T2DM, providing i...

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Bibliographic Details
Main Authors: Qianqian Ji, Yaxian Meng, Xiaojie Han, Chao Yi, Xiaoliang Chen, Yiqiang Zhan
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:The Clinical Respiratory Journal
Subjects:
chronic obstructive pulmonary disease
cross‐species validation
differentially expressed genes
machine learning
Type 2 diabetes mellitus
weighted gene co‐expression network analysis
Online Access:https://doi.org/10.1111/crj.70057
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https://doi.org/10.1111/crj.70057

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