Evaluating cholesterol de novo synthesis biomarkers: a systematic review and meta-analysis of cancer prognosis and clinical outcomes

Evaluating cholesterol de novo synthesis biomarkers: a systematic review and meta-analysis of cancer prognosis and clinical outcomes

Abstract Background While systemic cholesterol levels are generally associated with cancer risk and progression in various tumors, studies of cholesterol de novo synthesis by cancer cells in various tumor settings were limited. This meta-analysis aims to provide a comprehensive understanding of the...

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Bibliographic Details
Main Authors: Eman Taha Osman Ali, Nouh Saad Mohamed, Emmanuel Edwar Siddig, Mai Abdul Rahman Mohammed Masri
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Cancer
Subjects:
Cholesterol synthesis
Prognostic markers
Metabolic reprogramming
Solid tumors
Online Access:https://doi.org/10.1186/s12885-025-14633-8
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https://doi.org/10.1186/s12885-025-14633-8

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