TLR2 and TLR4 bridge physiological and pathological inflammation in the reproductive system

Abstract Toll-like receptors (TLRs), particularly TLR2 and TLR4, are critical components of the innate immune system that play significant roles in reproductive biology beyond their well-established functions in immune defense. These receptors recognize distinct pathogen-associated molecular pattern...

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Bibliographic Details
Main Authors: Alireza Mansouri, Ihshan Akthar, Akio Miyamoto
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08424-x
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