Human SLAM-adapted canine distemper virus can enter human peripheral blood mononuclear cells and replicate in mice expressing human SLAM and defective for STAT1 expression

Human SLAM-adapted canine distemper virus can enter human peripheral blood mononuclear cells and replicate in mice expressing human SLAM and defective for STAT1 expression

Canine distemper virus (CDV) is a member of the genus Morbillivirus with a worldwide distribution that causes fatal diseases in canids and marine mammals. In recent years, CDV has demonstrated the remarkable ability of pathogens to cross species barriers. The natural host range of CDV has expanded f...

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Bibliographic Details
Main Authors: Boyu Zhai, Wei Ran, Yiyang Sun, Angelita Alcos, Mengjia Liu, Jie Chen, Christopher D. Richardson, Dongbo Sun, Jianjun Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Virulence
Subjects:
Canine distemper virus
haemagglutinin
Cross-host transmission
human SLAM
transgenic mouse
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2025.2457967
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https://www.tandfonline.com/doi/10.1080/21505594.2025.2457967

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