Transient biopsy-proven progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome (PML-IRIS) in an elderly woman without known immunodeficiency: a case report

Transient biopsy-proven progressive multifocal leukoencephalopathy-immune reconstitution inflammatory syndrome (PML-IRIS) in an elderly woman without known immunodeficiency: a case report

Abstract Background Progressive multifocal leukoencephalopathy (PML) is a severe opportunistic brain disease caused by lytic JC polyomavirus (JCPyV) replication in oligodendrocytes. Although JCPyV infection is common in the general population, PML almost exclusively occurs in patients immunocompromi...

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Main Authors: Susanne Gaarden Ingebrigtsen, Kristin Smistad Myrmel, Stian Henriksen, Gry Charlotte Wikran, Marit Herder, Garth D. Tylden, Hans H. Hirsch, Christine Hanssen Rinaldo
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Neurology
Subjects:
JC polyomavirus
Progressive multifocal leukoencephalopathy
Immune reconstitution inflammatory syndrome
MRI
Brain biopsy
Flow cytometric immunophenotyping
Online Access:https://doi.org/10.1186/s12883-024-03945-0
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https://doi.org/10.1186/s12883-024-03945-0

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