Tocilizumab combined with cyclophosphamide for the treatment of rapidly progressive refractory systemic sclerosis with predominant cardiac involvement: a case report
Systemic sclerosis (SSc) with multi-organ involvement poses significant therapeutic challenges. We present a case of rapidly progressive, refractory SSc with cardiac, musculoskeletal, and skin manifestations that was successfully managed with a combination of cyclophosphamide (CYC) and tocilizumab (...
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| Main Authors: | Zhong-Chao Fu, Jing Ji, Xiao-Gui Cheng, Ran-Geng Shi, Xiao-Feng Mo, Zhi-Zhu Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1614714/full |
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