Tocilizumab combined with cyclophosphamide for the treatment of rapidly progressive refractory systemic sclerosis with predominant cardiac involvement: a case report

Systemic sclerosis (SSc) with multi-organ involvement poses significant therapeutic challenges. We present a case of rapidly progressive, refractory SSc with cardiac, musculoskeletal, and skin manifestations that was successfully managed with a combination of cyclophosphamide (CYC) and tocilizumab (...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhong-Chao Fu, Jing Ji, Xiao-Gui Cheng, Ran-Geng Shi, Xiao-Feng Mo, Zhi-Zhu Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1614714/full
Tags: Add Tag
No Tags, Be the first to tag this record!