DNA duplication in Burkholderia thailandensis induces biofilm formation by activating a two-component regulatory system.

Burkholderia thailandensis strain E264 (BtE264) and close relatives stochastically duplicate a 208.6 kb region of chromosome I via RecA-dependent recombination between two nearly identical insertion sequence elements. Because homologous recombination occurs at a constant, low level, populations of B...

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Bibliographic Details
Main Authors: Lillian C Lowrey, Katlyn B Mote, Peggy A Cotter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011528
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