Genetic influences on the association between DNA methylation and obesity measures: insights from a twin study design

Genetic influences on the association between DNA methylation and obesity measures: insights from a twin study design

Abstract Background Both obesity and DNA methylation (DNAm) are influenced by genetic factors. Despite more than a thousand of obesity-related DNAm sites (CpGs) being identified, studies that account for genetic influences in these associations are limited. Results Using data from 1,074 twins in the...

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Main Authors: Xuanming Hong, Hui Cao, Weihua Cao, Jun Lv, Canqing Yu, Tao Huang, Dianjianyi Sun, Chunxiao Liao, Yuanjie Pang, Runhua Hu, Ruqin Gao, Min Yu, Jinyi Zhou, Xianping Wu, Yu Liu, Shengli Yin, Wenjing Gao, Liming Li
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cell & Bioscience
Subjects:
DNA methylation
Obesity
Genetic correlations
Twin study
Online Access:https://doi.org/10.1186/s13578-025-01446-2
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https://doi.org/10.1186/s13578-025-01446-2

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