Lercanidipine Enhances Cisplatin Activity: Dual Anticancer and Anti-Inflammatory Effects via Caspase Activation and MAPK Inhibition

Lercanidipine Enhances Cisplatin Activity: Dual Anticancer and Anti-Inflammatory Effects via Caspase Activation and MAPK Inhibition

<b>Background/Objectives</b>: Lercanidipine is a third-generation dihydropyridine calcium channel blocker. In addition to their well-established cardiovascular effects, calcium channel blockers are increasingly recognized for their therapeutic potential in various cancers. This study aim...

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Bibliographic Details
Main Authors: Tugce Uskur, Sevde Nur Biltekin, Gokhan Faikoglu, Kubra Saygisever-Faikoglu, Barkın Berk
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceuticals
Subjects:
lercanidipine
cisplatin
cell culture
calcium channels
cancer
Online Access:https://www.mdpi.com/1424-8247/18/5/651
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