Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination

Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination

The emergence of SARS-CoV-2 recombinants is of particular concern as they can result in a sudden increase in immune evasion due to antigenic shift. Recent recombinants XBB and XBB.1.5 have higher transmissibility than previous recombinants such as “Deltacron.” We hypothesized that immunity to a SARS...

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Main Authors: Rahul K. Suryawanshi, Taha Y. Taha, Maria McCavitt-Malvido, Ines Silva, Mir M. Khalid, Abdullah M. Syed, Irene P. Chen, Prachi Saldhi, Bharath Sreekumar, Mauricio Montano, Kafaya Foresythe, Takako Tabata, G. Renuka Kumar, Alicia Sotomayor-Gonzalez, Venice Servellita, Amelia Gliwa, Jenny Nguyen, Noah Kojima, Teresa Arellanor, Aallyah Bussanich, Victoria Hess, Maria Shacreaw, Lauren Lopez, Matthew Brobeck, Fred Turner, Yuzhu Wang, Sydney Ghazarian, Gregg Davis, Diviana Rodriguez, Jennifer Doudna, Lee Spraggon, Charles Y. Chiu, Melanie Ott
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV-2
recombinants
humoral immunity
neutralization
vaccine
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2270071
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https://www.tandfonline.com/doi/10.1080/22221751.2023.2270071

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