Targeting SHMT2‐mediated membrane phospholipid remodeling for enhanced anti‐GCSCs treatment

Abstract Cancer stem cells exhibit flexible metabolic profiles. However, the underlying mechanisms for differential metabolic pathways affecting stemness maintenance in gastric cancer are poorly understood. Here, we reveal the role of serine hydroxymethyltransferase‐2 (SHMT2)/serine‐mediated crossta...

Full description

Saved in:
Bibliographic Details
Main Authors: Liping Yang, Fangli Liao, Yanran Tong, Tong Huang, Yan‐e Du, Siyang Wen, Linshan Jiang, Lanlang Peng, Hua Sun, Gaoli Zhang, Weixian Chen
Format: Article
Language:English
Published: Wiley-VCH 2025-05-01
Series:Interdisciplinary Medicine
Subjects:
Online Access:https://doi.org/10.1002/INMD.20240106
Tags: Add Tag
No Tags, Be the first to tag this record!