Optimizing polyphenol extraction and UPLC-MS/MS analysis from red clover (Trifolium pratense L.) species using response surface methodology

Polyphenols were extracted from red clover (Trifolium pratense L.) plants following conventional extraction. The combined factors of ethanol concentration (60–80%), extraction time (15–45 min) and extraction temperature (40–80°C) were evaluated. Central composite design software was used to conduct...

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Bibliographic Details
Main Authors: Emily P. Verhulst, Carlos Álvarez, Nigel P. Brunton, Dilip K. Rai
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Food Chemistry Advances
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772753X24002235
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