Cycle inhibiting factors (CIFs) are a growing family of functional cyclomodulins present in invertebrate and mammal bacterial pathogens.

Cycle inhibiting factors (CIFs) are a growing family of functional cyclomodulins present in invertebrate and mammal bacterial pathogens.

The cycle inhibiting factor (Cif) produced by enteropathogenic and enterohemorrhagic Escherichia coli was the first cyclomodulin to be identified that is injected into host cells via the type III secretion machinery. Cif provokes cytopathic effects characterized by G(1) and G(2) cell cycle arrests,...

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Main Authors: Grégory Jubelin, Carolina Varela Chavez, Frédéric Taieb, Mark J Banfield, Ascel Samba-Louaka, Rika Nobe, Jean-Philippe Nougayrède, Robert Zumbihl, Alain Givaudan, Jean-Michel Escoubas, Eric Oswald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0004855&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0004855&type=printable

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