Comparison of immune responses to SARS-CoV-2 spike following Omicron infection or Omicron BA.4/5 vaccination in kidney transplant recipients

Comparison of immune responses to SARS-CoV-2 spike following Omicron infection or Omicron BA.4/5 vaccination in kidney transplant recipients

BackgroundThe emergence of novel SARS-CoV-2 variants challenges immunity, particularly among immunocompromised kidney transplant recipients (KTRs). To address this, vaccines have been adjusted to circulating variants. Despite intensive vaccination efforts, SARS-CoV-2 infections surged among KTRs dur...

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Main Authors: Inga Tometten, Tobias Brandt, Maike Schlotz, Ricarda Stumpf, Sinje Landmann, Marta Kantauskaite, Joshua Lamberti, Jonas Hillebrandt, Lisa Müller, Margarethe Kittel, Katrin Ivens, Henning Gruell, Anja Voges, Heiner Schaal, Nadine Lübke, Eva Königshausen, Lars Christian Rump, Florian Klein, Johannes Stegbauer, Jörg Timm
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
Omicron BA.4/5
Omicron XBB.1.5
bivalent vaccination
kidney transplant recipients
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1476294/full
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