Quzhuo tongbi formula for reducing gout flare related to uric acid lowering treatment: Study protocol for a multiple-center, randomized, double-blind, placebo, parallel-controlled clinical trial.

Quzhuo tongbi formula for reducing gout flare related to uric acid lowering treatment: Study protocol for a multiple-center, randomized, double-blind, placebo, parallel-controlled clinical trial.

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<h4>Introduction</h4>Gout, a prevalent metabolic rheumatic disease, arises from the accumulation of monosodium urate (MSU) crystals in joints, directly associated with hyperuricemia. Long-term or lifelong urate-lowering therapy (ULT) stands as the primary management strategy. However, th...

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Main Authors: Hejing Pan, Xuanlin Li, Shan Wu, Donghai Zhou, Haojie Guan, Haoyu Wu, Qiao Wang, Yujun Tang, Xuanming Hu, Meijiao Wang, Mingqian Zhou, Runyue Huang, Lei Liu, Yaolong Chen, Chengping Wen, Lin Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0327864
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https://doi.org/10.1371/journal.pone.0327864

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