Exploring the sequence diversity and surface expression of Factor H-Binding Protein among invasive serogroup B meningococcal strains from selected European countries

Factor H-Binding Protein (fHbp) is a key component of meningococcal vaccines such as MenB-fHbp, licensed in the EU, UK, and other countries. Sufficient expression of fHbp on the bacterial surface is necessary for vaccine-induced antibodies to bind and exert bactericidal activity. The flow cytometric...

Full description

Saved in:
Bibliographic Details
Main Authors: Stephen A. Clark, Laura Willerton, Heike Claus, Anna Carannante, Paola Stefanelli, Raquel Abad, Julio A. Vázquez, Ray Borrow
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2427471
Tags: Add Tag
No Tags, Be the first to tag this record!