GENERATION OF CD34+ DERIVED HUMAN MACROPHAGE EXPRESSING CHIMERIC ANTIGEN RECEPTORS FOR CANCER TREATMENT

Objective: T lymphocytes expressing Chimeric Antigen Receptor (CAR) has proven to be an auspicious strategy in treatment of hematological malignancies, but with low efficacy in solid tumors due to their complex microenvironment. From this perspective, macrophages become promising cells for CAR inser...

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Bibliographic Details
Main Authors: Ian-Costa, Livia-Furquin, Viviane-Jennifer, Théo-Gremen, Samuel-Campanelli, Rafael-Almeida, Vanderson-Rocha, Rodrigo-Nalio
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S253113792402025X
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