TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes.

TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes.

In developing melanocytes and in melanoma cells, multiple paralogs of the Activating-enhancer-binding Protein 2 family of transcription factors (TFAP2) contribute to expression of genes encoding pigmentation regulators, but their interaction with Microphthalmia transcription factor (MITF), a master...

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Bibliographic Details
Main Authors: Colin Kenny, Ramile Dilshat, Hannah E Seberg, Eric Van Otterloo, Gregory Bonde, Annika Helverson, Christopher M Franke, Eiríkur Steingrímsson, Robert A Cornell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010207&type=printable
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https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010207&type=printable

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