Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents.

Α-galactosylceramide analogs with weak agonist activity for human iNKT cells define new candidate anti-inflammatory agents.

CD1d-restricted natural killer T cells with invariant T cell receptor α chains (iNKT cells) are a unique lymphocyte subset that responds to recognition of specific lipid and glycolipid antigens. They are conserved between mice and humans and exert various immunoregulatory functions through their rap...

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Main Authors: Gabriel Bricard, Manjunatha M Venkataswamy, Karl O A Yu, Jin S Im, Rachel M Ndonye, Amy R Howell, Natacha Veerapen, Petr A Illarionov, Gurdyal S Besra, Qian Li, Young-Tae Chang, Steven A Porcelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0014374&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0014374&type=printable

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