A vascularized tumors-on-a-chip model for studying tumor-angiogenesis interplay, heterogeneity and drug responses

A vascularized tumors-on-a-chip model for studying tumor-angiogenesis interplay, heterogeneity and drug responses

Current tumor models struggle to replicate the complexity of the tumor microenvironment, particularly endothelial sprouting and vascular-tumor interactions. To address these limitations, we developed a vascularized tumors-on-a-chip model by fusing tumor spheroids with HUVEC spheroids to simulate ang...

Full description

Saved in:
Bibliographic Details
Main Authors: Suyeon Shin, Yurim Choi, WonJun Jang, Batjargal Ulziituya, Giheon Ha, Raehui Kang, Soojin Park, Minseok Kim, Yu Shrike Zhang, Han-Jun Kim, Junmin Lee
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
Subjects:
Tumor-vessel interaction
Vascularized tumor model
Tumor microenvironment (TME)
Tumors-on-a-chip
Online Access:http://www.sciencedirect.com/science/article/pii/S259000642500300X
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S259000642500300X

Similar Items