Systemic stem cell treatment rescues injured motoneurons by reducing L-selectin expression on leukocytes

Systemic stem cell treatment rescues injured motoneurons by reducing L-selectin expression on leukocytes

Abstract Background Avulsion injury results in motoneuron death due to the increased cytotoxicity developing after the injury. We have earlier shown that intraspinally grafted immortalized NE-4C neuroectodermal stem cells derived from 9-day old mouse forebrain vesicles produced a secretome, which in...

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Main Authors: Tamás Bellák, Zoltán Fekécs, Dénes Török, Rebeka Kristóf, Omoikhoje Esezoobo, Annamária Marton, Csaba Vizler, Antal Nógrádi, Krisztián Pajer
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Stem Cell Research & Therapy
Subjects:
Motoneuron injury
Stem cells
Fucoidan
Neuroinflammation
Regeneration
Functional recovery
Online Access:https://doi.org/10.1186/s13287-025-04283-9
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https://doi.org/10.1186/s13287-025-04283-9

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