Phosphatase UBLCP1 is required for the growth, virulence and mitochondrial integrity of Toxoplasma gondii

Phosphatase UBLCP1 is required for the growth, virulence and mitochondrial integrity of Toxoplasma gondii

Abstract Background The mitochondrion is proposed as an ideal target organelle for the control of apicomplexan parasites, whose integrity depends on well-controlled protein import, folding, and turnover. The ubiquitin-like domain-containing C-terminal domain phosphatase 1 (UBLCP1) was found to be as...

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Bibliographic Details
Main Authors: Kaiyin Sheng, Kaiyue Song, Yimin Yang, Haiyan Wu, Zhendong Du, Xueqiu Chen, Yi Yang, Guangxu Ma, Aifang Du
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Parasites & Vectors
Subjects:
Toxoplasma gondii
UBLCP1
Mitochondrial integrity
Pathogenicity
Vaccine candidate
Online Access:https://doi.org/10.1186/s13071-025-06766-3
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https://doi.org/10.1186/s13071-025-06766-3

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