Temporal Changes Toward Cellular Senescence in Rat Dental Pulp Stem Cells Induced by Long-Term In Vitro Culture

Temporal Changes Toward Cellular Senescence in Rat Dental Pulp Stem Cells Induced by Long-Term In Vitro Culture

Rat dental pulp stem cells (DPSCs) can be used to elucidate mesenchymal stem cell (MSC) applications in regenerative medicine. However, information on rat DPSCs during long-term passage, which could lead to replicative senescence, is limited. In this study, we investigated the phenotypic changes in...

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Bibliographic Details
Main Authors: Shanshan Zheng, Masato Nakagawa, Yanan Gong, Yasuhiko Matsushima, Satoshi Sasayama, Shunsuke Baba, Yoshitomo Honda
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Applied Sciences
Subjects:
dental pulp stem cell
cellular senescence
senescence markers
long-term culture
Online Access:https://www.mdpi.com/2076-3417/14/23/11376
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https://www.mdpi.com/2076-3417/14/23/11376

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