Quantitative chemical proteomics reveals that phenethyl isothiocyanate covalently targets BID to promote apoptosis

Abstract Naturally occurring isothiocyanates (ITCs) found in cruciferous vegetables, such as benzyl isothiocyanate (BITC), phenethyl isothiocyanate (PEITC), and sulforaphane (SFN), have attracted significant research interest for their promising anti-cancer activity in vitro and in vivo. While the i...

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Bibliographic Details
Main Authors: Xiaoshu Dong, Xinqian Yu, Minghao Lu, Yaxin Xu, Liyan Zhou, Tao Peng
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02225-7
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