Quantification of liver fat fraction using T1-weighted mDixon MRI in young patients with ataxia telangiectasia undergoing whole-body MRI: an exploratory study

Quantification of liver fat fraction using T1-weighted mDixon MRI in young patients with ataxia telangiectasia undergoing whole-body MRI: an exploratory study

Abstract Background Ataxia–telangiectasia (A–T) is an inherited multiorgan disorder with onset in childhood. Liver involvement, with steatosis and subsequent fibrosis, is increasingly recognized in children and young people with A–T. Purpose To evaluate feasibility of T1-weighted two-point mDixon MR...

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Bibliographic Details
Main Authors: Soma Kumasaka, Rafal Panek, Renata Neves, Mohnish Suri, Sumit Jagani, Yuka Kumasaka, Yoshito Tsushima, Robert A. Dineen
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Ataxia–telangiectasia (A–T)
Steatosis
Fat fraction
MRI
Dixon
Online Access:https://doi.org/10.1186/s13023-025-03786-1
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https://doi.org/10.1186/s13023-025-03786-1

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