Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes

Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes

Abstract Despite the availability of several large‐scale proteomics studies aiming to identify protein interactions on a global scale, little is known about how proteins interact and are organized within macromolecular complexes. Here, we describe a technique that consists of a combination of bioche...

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Bibliographic Details
Main Authors: Kenneth K Lee, Mihaela E Sardiu, Selene K Swanson, Joshua M Gilmore, Michael Torok, Patrick A Grant, Laurence Florens, Jerry L Workman, Michael P Washburn
Format: Article
Language:English
Published: Springer Nature 2011-07-01
Series:Molecular Systems Biology
Subjects:
ADA
architecture
protein interaction network
quantitative proteomics
SAGA
Online Access:https://doi.org/10.1038/msb.2011.40
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https://doi.org/10.1038/msb.2011.40

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