Colorectal cancer screening using a multi-locus blood-based assay targeting circulating tumor DNA methylation: a cross-sectional study in an average-risk population

Colorectal cancer screening using a multi-locus blood-based assay targeting circulating tumor DNA methylation: a cross-sectional study in an average-risk population

Abstract Background Effective screening for colorectal cancer (CRC) enables earlier diagnosis and intervention to improve patient survival. Methods In this study, we prospectively conducted a blood-based CRC screening program for community residents in Hanjiang District, Yangzhou City, and evaluated...

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Main Authors: Baohua Wang, Yunzhi Zhang, Jun Liu, Bin Deng, Qing Li, Hongmei Liu, Yi Sui, Ning Wang, Qin Xiao, Wei Liu, Yan Chen, Yongsheng Li, Haipeng Jia, Qilong Yuan, Cuiping Wang, Wenjun Pan, Fan Li, Huimin Yang, Yongfeng Wang, Yanbing Ding, Daoliang Xu, Rui Liu, Jing-Yuan Fang, Jing Wu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Medicine
Subjects:
Colorectal cancer
Population-based screening
Blood-based ctDNA detection
Risk factor questionnaire assessment
Online Access:https://doi.org/10.1186/s12916-024-03777-2
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https://doi.org/10.1186/s12916-024-03777-2

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