Quantitative Determination of Lentiviral Vector Particle Numbers by Real-Time PCR

Here, we describe a quantitative, DNAbased, real-time PCR approach to determine the number of lentivirus particles that are present in vector preparations. In this approach, the minus strong-stop cDNA fragment that is present in viral capsids serves as template for PCR. Using this technology, we fou...

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Bibliographic Details
Main Authors: M. Scherr, K. Battmer, U. Blömer, A. Ganser, M. Grez
Format: Article
Language:English
Published: Taylor & Francis Group 2001-09-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/01313st05
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