Hydrogen Sulfide Promotes TAM‐M1 Polarization through Activating IRE‐1α Pathway via GRP78 S‐Sulfhydrylation to against Breast Cancer

Hydrogen Sulfide Promotes TAM‐M1 Polarization through Activating IRE‐1α Pathway via GRP78 S‐Sulfhydrylation to against Breast Cancer

Abstract Hydrogen sulfide (H2S)‐mediated protein S‐sulfhydration has been shown to play critical roles in several diseases. Tumor‐associated macrophages (TAMs) are the predominant population of immune cells present within solid tumor tissues, and they function to restrict antitumor immunity. However...

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Bibliographic Details
Main Authors: Mingyi Ju, Weiwei Tong, Jia Bi, Xianxin Zeng, Aoshuang Qi, Mingli Sun, Jian Wen, Lin Zhao, Minjie Wei
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
breast cancer
hydrogen sulfide
macrophage repolarization
S‐sulfhydrylation
tumor‐associated macrophages
Online Access:https://doi.org/10.1002/advs.202413607
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https://doi.org/10.1002/advs.202413607

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