D-mannose promotes diabetic wound healing through inhibiting advanced glycation end products formation in keratinocytes

D-mannose promotes diabetic wound healing through inhibiting advanced glycation end products formation in keratinocytes

Abstract Background Diabetic chronic foot ulcers pose a significant therapeutic challenge around the world, resulting in adverse effects and complications in patients. D-mannose is enriched in cirtus peel and exerts beneficial effects among various diseases, especially against inflammation-related d...

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Bibliographic Details
Main Authors: Jialiang Luo, Tianxing Wu, Jing Zhang, Zhicheng Liang, Weijie Shao, Di Wang, Lei Li, Daming Zuo, Jia Zhou
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Molecular Medicine
Subjects:
D-mannose
Diabetic wound healing
AGEs formation
Keratinocytes
AMPK/Nrf2/HO-1 signaling
Online Access:https://doi.org/10.1186/s10020-025-01070-3
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https://doi.org/10.1186/s10020-025-01070-3

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