Histological and immunohistochemical approaches to molecular subtyping in muscle-invasive bladder cancer

Histological and immunohistochemical approaches to molecular subtyping in muscle-invasive bladder cancer

Muscle-invasive bladder cancer (MIBC) is an aggressive form of bladder cancer, representing 20–25% of all bladder cancer cases. Characterized by invasion into the detrusor muscle, MIBC often leads to high rates of metastasis and poor outcomes, with five-year survival rates below 50% for localized di...

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Bibliographic Details
Main Authors: Giulio Attanasio, Maria Failla, Simone Poidomani, Tindaro Buzzanca, Serena Salzano, Maurizio Zizzo, Andrea Palicelli, Magda Zanelli, Nektarios Koufopoulos, Giorgio Ivan Russo, Rosario Caltabiano, Giuseppe Broggi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
muscle-invasive
molecular subtypes
immunohistochemistry
diagnosis
bladder cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1546160/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1546160/full

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