Identification of three T cell-related genes as diagnostic and prognostic biomarkers for triple-negative breast cancer and exploration of potential mechanisms

Identification of three T cell-related genes as diagnostic and prognostic biomarkers for triple-negative breast cancer and exploration of potential mechanisms

BackgroundTriple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer (BRCA) with limited therapeutic targets. This study aimed to identify T cell-related signatures for TNBC diagnosis and prognosis.MethodsClinical data and transcriptomic profiles were obtained from the TCGA-BRCA...

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Bibliographic Details
Main Authors: Zhi-Chuan He, Zheng-Zheng Song, Zhe Wu, Peng-Fei Lin, Xin-Xing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Genetics
Subjects:
Triple-negative breast cancer
T cell-related genes
diagnosis
prognosis
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2025.1584334/full
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https://www.frontiersin.org/articles/10.3389/fgene.2025.1584334/full

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