Quercetin prevents the loss of chondrogenic capacity in expansion cultured human auricular chondrocytes by alleviating mitochondrial dysfunction

Quercetin prevents the loss of chondrogenic capacity in expansion cultured human auricular chondrocytes by alleviating mitochondrial dysfunction

Objective: To explore the characteristics of cellular senescence in human auricular chondrocytes during long-term in vitro culture and to evaluate the effects of anti-senescence treatments on enhancing their chondrogenic function. Methods: Auricular chondrocytes exhibited senescence-related characte...

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Bibliographic Details
Main Authors: Hua Tong, Xudong Guo, Lili Chen, Honglei Wang, Xuerui Hu, Aijuan He, Chenlong Li, Tianyu Zhang, Jiuhong Kang, Yaoyao Fu
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Regenerative Therapy
Subjects:
Tissue engineering
Chondrocytes
Senescence
Mitochondrial dysfunction
Quercetin
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320425000057
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