Metronidazole induces genotoxicity, hepato- and nephrotoxicity by triggering DNA fragmentation in Swiss albino mice (Balb/c)

Abstract In this study, toxic effects of metronidazole (Mtz) on albino mice, a non-target organism, were investigated using organ weight, genotoxicity assays, serum markers, liver and kidney histopathology. Mice were administered three different doses of Mtz (125–500 mg/kg, 250 mg/kg and 500 mg/kg)...

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Bibliographic Details
Main Authors: Tuana Rana Topal, Mehmet Karan, Kültiğin Çavuşoğlu, Emine Yalçın
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-12230-0
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