An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis

An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis

Abstract Atherosclerosis is the underlying cause of myocardial infarction and ischemic stroke. It is a lipid-triggered and cytokine/chemokine-driven arterial inflammatory condition. We identify D-dopachrome tautomerase/macrophage migration-inhibitory factor-2 (MIF-2), a paralog of the cytokine MIF,...

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Main Authors: Omar El Bounkari, Chunfang Zan, Bishan Yang, Simon Ebert, Jonas Wagner, Elina Bugar, Naomi Kramer, Priscila Bourilhon, Christos Kontos, Marlies Zarwel, Dzmitry Sinitski, Jelena Milic, Yvonne Jansen, Wolfgang E. Kempf, Nadja Sachs, Lars Maegdefessel, Hao Ji, Ozgun Gokce, Fabien Riols, Mark Haid, Simona Gerra, Adrian Hoffmann, Markus Brandhofer, Maida Avdic, Richard Bucala, Remco T. A. Megens, Nienke Willemsen, Denise Messerer, Christian Schulz, Alexander Bartelt, Tobias Harm, Dominik Rath, Yvonne Döring, Meinrad Gawaz, Christian Weber, Aphrodite Kapurniotu, Jürgen Bernhagen
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57540-z
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https://doi.org/10.1038/s41467-025-57540-z

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