Quantifying lactulose and mannitol using LC-MS/MS in a clinical study of children with environmental enteric disease

Quantifying lactulose and mannitol using LC-MS/MS in a clinical study of children with environmental enteric disease

Dysfunction of the intestinal epithelium barrier (DIEB) is frequent and can lead to serious complications in early childhood when diagnosis and clinical intervention are limited, especially in children with environmental enteric disease and malnutrition. The use of refined analytical techniques is i...

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Main Authors: L.M.V.C. Magalhães, F.A.P. Rodrigues, J.Q. Filho, R.N.D.G. Gondim, S.A. Ribeiro, T.B.M. Rôla, M.A.F. Clementino, B.L.L. Maciel, P.J.C. Magalhães, A. Havt, A.A. Santos, A.A.M. Lima
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2025-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Environmental enteric disease
Intestinal epithelium barrier function
Lactulose mannitol permeability test
Intestinal epithelium dysfunction
Liquid chromatography coupled with tandem mass spectrum
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2025000100624&lng=en&tlng=en
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