Nonlinearity of optoacoustic signals and a new contrast mechanism for imaging

Abstract Optoacoustic signals behave nonlinearly at light fluences above a few mJ/cm2, which may affect the interpretation and quantification of measurements. It has been proposed that optoacoustic nonlinearity arises from the heat-induced formation of nanobubbles or changes in local thermo-physical...

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Bibliographic Details
Main Authors: Jaber Malekzadeh-Najafabadi, Jaya Prakash, Daniel Razansky, Jorge Ripoll, Vipul Gujrati, Vasilis Ntziachristos
Format: Article
Language:English
Published: Nature Publishing Group 2025-03-01
Series:Light: Science & Applications
Online Access:https://doi.org/10.1038/s41377-025-01772-7
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