Induction of autophagy in one-cell stage somatic cell nuclear transfer embryos improves preimplantation embryonic development in goat species.

Autophagy is a lysosome-mediated catabolic pathway that is dependent on the mammalian target of rapamycin (mTOR). It plays a crucial role in the degradation of aged organelles and macromolecules. Several studies have explored the role of autophagy in embryonic genome activation and its significance...

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Main Authors: Nasrin Mahvash, Reza Moradi-Hajidavaloo, Farnoosh Jafarpour, Mehdi Hajian, Mohsen Rahimi, Nafiseh Sanei Ata-Abadi, Marjan Sadeghi, Mohammad Hossein Nasr-Esfahani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0314176
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