Deficient of glycosylation site in the envelop protein attenuated Zika virus replication in mosquito cells

Deficient of glycosylation site in the envelop protein attenuated Zika virus replication in mosquito cells

IntroductionThe Zika virus (ZIKV) envelope (E) protein is critical for viral replication and host interactions. Although glycosylation of the E protein is known to influence viral infectivity and immune evasion, the specific functional roles of E protein glycosylation in ZIKV infectivity in mosquito...

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Main Authors: Wen-Jing Wang, Zi-Han Wang, Jing Li, Sai-Ya Ma, Mei He, Meng-Xuan Liu, Yu-Fei Zhan, Feng Jin, Guosheng Qu, Chunhong Yin, Jie Tong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Microbiology
Subjects:
Zika virus
E glycoprotein
mosquito cells
ECM signaling pathway
E-dimer
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1603083/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1603083/full

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